A lineage with no living descendants
Here we go again:
DNA from a 7,200 year old woman found in cave reveals a completely unknown human lineage
5/7/2026In 2015, University of Hasanuddin archaeologists discovered a young woman's skeleton inside Sulawesi’s Leang Panninge limestone cave. The 7,200 year old remains were found in a fetal position alongside stone tools and animal bones. Excavators nicknamed her Bessé, honoring a local Bugis royal custom for newborn princesses. Analysis suggests she died at approximately 17 or 18 years of age. Sheltered by stone layering, her bones remained intact until their recovery.
A study in Nature identifies Bessé as a member of the Toalean culture. These hunter-gatherers occupied Sulawesi’s southwestern peninsula between 8,000 and 1,500 years ago. She represents the first relatively complete skeleton linked to that culture. Her remains yielded genomic data that added a new branch to the human family tree.
DNA from the deep tropics
Extracting ancient DNA from tropical remains is difficult because heat and humidity degrade genetic material fast. Lead author Selina Carlhoff isolated DNA from the individual’s petrous bone. This dense structure at the skull’s base preserves genetic material more effectively than other remains.
“It was a major challenge, as the remains had been strongly degraded by the tropical climate,” she said.
Specifically, the team recovered around 2% of Bessé’s complete genome, enough to analyse her ancestry in detail. This makes Bessé’s genome the first ancient human DNA recovered from Wallacea, the archipelago of islands between Borneo and New Guinea that served as the migration corridor to Australia.

An unexpected ancestral signature
Bessé’s genome shares significant genetic drift with present-day Aboriginal Australians and Papuans. This lineage includes DNA from Denisovans, an archaic human group distinct from Neanderthals. Consequently, these genetic markers link her directly to populations across the western Pacific. That connection supports the hypothesis that the Toaleans descended from the earliest wave of modern humans to cross Wallacea, reaching what scientists call Sahul, the Pleistocene supercontinent that united Australia, Tasmania, and New Guinea when sea levels fell.
“They were the first inhabitants of Sahul, the supercontinent that emerged during the Pleistocene when the global level of the oceans fell,” said co-study leader Professor Adam Brumm of Griffith University.
Yet Bessé’s genome also carried a deep Asian ancestral indicator that no known population, ancient or modern, accounts for. Until now, scientists knew of only one documented migration of modern humans from Asia into Wallacea, the Austronesian expansion roughly 3,500 years ago. Bessé predates that by more than 3,700 years, which means her ancestors represent a separate and previously unrecognised wave of human movement into the region.

A lineage with no living descendants
The team found no match between Bessé’s ancestry and that of any current Sulawesi population. Modern inhabitants of the island descend primarily from Neolithic farmers who arrived approximately 3,500 years ago, and none carries a genetic signature resembling hers.
“Bessé’s ancestors did not mix with those of Australian Aboriginals and Papuans,” said Brumm and colleagues in The Conversation, “suggesting they arrived after the initial settlement of Sahul but well before the Austronesian expansion.”
The Toalean culture itself left almost no trace in the region’s present day gene pool, suggesting the group remained isolated for millennia before disappearing around 1,500 years ago.
Scientists hope that further genetic analysis of Sulawesi’s modern population may yet recover traces of Toalean ancestry. New excavations at Leang Panninge are also planned. Bessé’s genome doesn’t just reveal a forgotten people. It shows that the early human settlement of island Southeast Asia involved more distinct migrations, at far earlier dates, than the current record has captured.
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